BDBM448070 US10689395, Compound b::US11267820, Compound b

SMILES CCNC(=O)CC1N=C(c2c(C)c(C)sc2-c2cn(C)c(=O)cc12)c1ccc(Cl)cc1

InChI Key InChIKey=JMWGJVUSJIRXCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448070   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448070(US10689395, Compound b | US11267820, Compound b)
Affinity DataIC50:  2.20nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448070(US10689395, Compound b | US11267820, Compound b)
Affinity DataIC50:  2.20nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent