BDBM448075 US10689395, Compound e::US11267820, Compound e

SMILES Cc1sc-2c(c1C)C(=NC(CC(N)=O)c1cc(=O)n(C)cc-21)c1ccc(Cl)cc1

InChI Key InChIKey=HGQVXIHUUVUMHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448075   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448075(US10689395, Compound e | US11267820, Compound e)
Affinity DataIC50:  2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448075(US10689395, Compound e | US11267820, Compound e)
Affinity DataIC50:  2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent