BDBM448077 US10689390, Compound 28::US11319326, Compound 28

SMILES COc1ccc2-c3cn(C)c(=O)cc3C(CC(N)=O)N=C(c3ccc(Cl)cc3)c2c1

InChI Key InChIKey=OVWBTWXDFMHNPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448077   

TargetBromodomain-containing protein 4 [44-168](Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448077(US10689390, Compound 28 | US11319326, Compound 28)
Affinity DataIC50:  36nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448077(US10689390, Compound 28 | US11319326, Compound 28)
Affinity DataIC50:  36nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent