BDBM448190 (R)-8-benzyl-13-ethyl-4-oxa-8,13-diazadispiro[2.1.3]tetradecan-14-one and (S)-8-benzyl-13-ethyl-4-oxa-8,13-diazadispiro[2.1.6.3]tetradecan-14-one::US10689398, Example 92::US10689398, Example 93

SMILES CCN1C[C@]2(CCCN(Cc3ccccc3)CC2)OC2(CC2)C1=O

InChI Key InChIKey=NBGKEOUVHIEVLT-LJQANCHMSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448190   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM448190((R)-8-benzyl-13-ethyl-4-oxa-8,13-diazadispiro[2.1....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM448190((R)-8-benzyl-13-ethyl-4-oxa-8,13-diazadispiro[2.1....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent