BDBM448341 USRE48059, Compound of Example 163

SMILES Clc1cc2CCC(=C)Nc2c(Cl)c1CCCN1CCN(CC1)c1cccc2sccc12

InChI Key InChIKey=IALCUIBHTWQWLY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448341   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM448341(USRE48059, Compound of Example 163)
Affinity DataKi:  2.80nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM448341(USRE48059, Compound of Example 163)
Affinity DataKi:  7.40nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent