BDBM448421 1-[(6-{3-Azabicyclo[4.1.0]heptan-3-yl}-2-methylpyridin-3-yl)methyl]-N-[(6R)-3-methyl-2H,4H,5H,6H-::US10695334, Example 48

SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC3CC3C2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448421   

TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448421(1-[(6-{3-Azabicyclo[4.1.0]heptan-3-yl}-2-methylpyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent