BDBM448425 1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyridin-3-yl)methyl]-N-[(6R)-3-methyl-1H,4H,5H,6H- cyclopenta[c]pyrazol-6-yl]-1H-1,2,3-triazole-4-carboxamide::US10695334, Example 86
SMILES Cc1c2CC[C@@H](NC(=O)c3cn(Cc4ccc(nc4C)N4CC5CC5C4)nn3)c2nn1COCC[Si](C)(C)C
InChI Key InChIKey=GRSUDZGETOEQQJ-UBVWURDFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 448425
Affinity DataIC50: >1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair