BDBM448431 1-({6-[(1R,5S,6R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-methylpyridin-3-yl}methyl)-N-[(6R)- 3-methyl-1H,4H,5H,6H-cyclopenta[c]pyrazol-6-yl]-1H-pyrazole-4-carboxamide::US10695334, Example 94
SMILES Cc1c2CC[C@@H](NC(=O)c3cnn(Cc4ccc(nc4C)N4C[C@H]5[C@@H](CO)[C@H]5C4)c3)c2nn1COCC[Si](C)(C)C
InChI Key InChIKey=JIMFFGPZQNHMHY-HVWQDESWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 448431
Affinity DataIC50: >1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair