BDBM448451 US10695347, Compound I-17

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CC(C)OC(C)C1

InChI Key InChIKey=IJZVJRVLQBAJAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448451   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute

US Patent
LigandPNGBDBM448451(US10695347, Compound I-17)
Affinity DataIC50:  5.5nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute

US Patent
LigandPNGBDBM448451(US10695347, Compound I-17)
Affinity DataIC50:  5.5nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent