BDBM448606 7-(2-(difluoromethyl)-6-methyl-3-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-methyl-2,3-dihydrobenzo[f][1,4]oxazepine-4(5H)-carboxamide::US10696655, Example 76::US11168070, Example 76

SMILES CNC(=O)N1CCOc2ccc(cc2C1)-c1c(C)ccc(-c2cnn(C)c2)c1C(F)F

InChI Key InChIKey=LDXFEXXYTYELDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448606   

TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448606(7-(2-(difluoromethyl)-6-methyl-3-(1-methyl-1H-pyra...)
Affinity DataIC50:  243nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448606(7-(2-(difluoromethyl)-6-methyl-3-(1-methyl-1H-pyra...)
Affinity DataIC50:  243nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent