BDBM449108 Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- acetyl-piperidine-4- sulfonyl)-benzylamide::US10696692, Example 229::US10696692, Example 86

SMILES CC(=O)N1CCC(CC1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3nccn3c2)cc1

InChI Key InChIKey=NYZZKELRDMRAIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449108   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449108(Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...)
Affinity DataIC50:  5.12nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449108(Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...)
Affinity DataIC50:  5.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent