BDBM449108 Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- acetyl-piperidine-4- sulfonyl)-benzylamide::US10696692, Example 229::US10696692, Example 86
SMILES CC(=O)N1CCC(CC1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3nccn3c2)cc1
InChI Key InChIKey=NYZZKELRDMRAIC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 449108
Affinity DataIC50: 5.12nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair