BDBM449185 US10696692, Example 164::cis-Imidazo[1,2- alpyridine-6-carboxylic acid 4-(5-fluoro-2-aza- bicyclo[2.2.1]heptane-2- sulfonyl)-benzylamide (racemic)

SMILES FC1CC2CC1CN2S(=O)(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1

InChI Key InChIKey=KXXBMMUSCGODAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449185   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449185(US10696692, Example 164 | cis-Imidazo[1,2- alpyrid...)
Affinity DataIC50:  8.10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent