BDBM450265 US10676431, Example 28::US11117861, Example 28

SMILES Cn1ccc(n1)-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F

InChI Key InChIKey=PUPIRVKPAFCYON-MRXNPFEDSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450265   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450265(US10676431, Example 28 | US11117861, Example 28)
Affinity DataEC50:  9.80nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450265(US10676431, Example 28 | US11117861, Example 28)
Affinity DataEC50:  550nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450265(US10676431, Example 28 | US11117861, Example 28)
Affinity DataEC50:  9.80nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450265(US10676431, Example 28 | US11117861, Example 28)
Affinity DataEC50:  550nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent