BDBM450396 2-[6-(4- Acetylpiperazin-1- yl)-4- oxoquinazolin-3- yl]acetic acid (intermediate A-2) and (4-fluorophenyl) methanamine ([CAS RN 140-75-0])::US10676446, Example 14
SMILES CC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(F)cc3)c(=O)c2c1
InChI Key InChIKey=FGGXEHKXJRBDIK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450396
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 1.47E+3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair