BDBM450405 2-[6-(4- Acetylpiperazin-1- yl)-4- oxoquinazolin-3- yl]acetic acid (intermediate A-2) and (3,4- dichlorophenyl) methanamine ([CAS RN 102-49-8])::US10676446, Example 22
SMILES CC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1
InChI Key InChIKey=JNMDSFYWQLLDAB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450405
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 91nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair