BDBM450439 2-[6-[4-(9H- Fluoren-9- ylmethoxycarbonyl) piperazin-1-yl]- 4-oxoquinazolin- 3-yl]acetic acid (intermediate A-1) and [5-(4- chlorophenyl)- 1,2,4-oxadiazol-3- yl]methanamine ([CAS RN 919750-83-7])::US10676446, Example 51

SMILES CC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3noc(n3)-c3ccc(Cl)cc3)c(=O)c2c1

InChI Key InChIKey=VCGFRHPGSWVRFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450439   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450439(2-[6-[4-(9H- Fluoren-9- ylmethoxycarbonyl) piperaz...)
Affinity DataIC50:  51nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent