BDBM450483 4-[3-[2-[(3,4-Dichlorophenyl)methylamino]-2-oxoethyl]-4-oxoquinazolin-6-yl]-N-propan-2-ylpiperazine-1-carboxamide::US10676446, Example 82

SMILES CC(C)NC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=KTSPAELZEIOVCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450483   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450483(4-[3-[2-[(3,4-Dichlorophenyl)methylamino]-2-oxoeth...)
Affinity DataIC50:  43nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent