BDBM450485 US10676446, Example 83
SMILES Clc1ccc(CNC(=O)Cn2cnc3ccc(cc3c2=O)N2CCN(CC2)C(=O)NC2CC2)cc1Cl
InChI Key InChIKey=ZHNMTKWVIXAADK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450485
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 30nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair