BDBM450495 N-[(3,4-Dichlorophenyl)methyl]-2-[6-(4-methylsulfonylpiperazin-1-yl)-4-oxoquinazolin-3-yl]acetamide::US10676446, Example 88
SMILES CS(=O)(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1
InChI Key InChIKey=WXLOYJSKFQWOHT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450495
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 88nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair