BDBM450506 9H-Fluoren-9- ylmethyl 4-[3-[2- [(3,4- dichlorophenyl) methylamino]-2- oxoethyl]-4- oxoquinazolin-6- yl]piperazine-1- carboxylale (intermediate A-5) and 1-::US10676446, Example 99
SMILES Cn1cccc1CN1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1
InChI Key InChIKey=IHNLYTZSVROHQE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450506
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 31nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair