BDBM450562 N-Cyclopropyl-N-[(3,4-dichlorophenyl)methyl]-2-[6-[1-(2-methoxyacetyl)piperidin-4-yl]-4-oxoquinazolin-3-yl]acetamide::US10676446, Example 146
SMILES COCC(=O)N1CCC(CC1)c1ccc2ncn(CC(=O)N(Cc3ccc(Cl)c(Cl)c3)C3CC3)c(=O)c2c1
InChI Key InChIKey=OERODERTWKPXHB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450562
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair