BDBM450566 1-[6-(4-Acetylpiperazin-1-yl)-4-oxoquinazolin-3-yl]-N-[(3,4-dichlorophenyl)methyl]cyclopropane-1-carboxamide::US10676446, Example 150
SMILES CC(=O)N1CCN(CC1)c1ccc2ncn(c(=O)c2c1)C1(CC1)C(=O)NCc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=GVCQGGVZHVNEFN-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450566
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 91nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair