BDBM450569 2-[6-(4-Acetylpiperazin-1-yl)-4-oxoquinazolin-3-yl]-N-[1-(3,4-dichlorophenyl)-3-methoxypropyl]acetamide::US10676446, Example 153
SMILES COCCC(NC(=O)Cn1cnc2ccc(cc2c1=O)N1CCN(CC1)C(C)=O)c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=SYMGHPZKUJPDDL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450569
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 36nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair