BDBM450612 Sodium (2S,3R)-3-((R or S)-2-(1-(2,5-bis(trifluoromethyl)benzyl)piperidin-4-yl)-1,2,3,4-tetrahydroquinolin-7-yl)-3-cyclopropyl-2-methylpropanoate::US10676458, Example 6::US10676458, Example 7

SMILES C[C@@H]([C@@H](C1CC1)c1ccc2CCC(Nc2c1)C1CCN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)CC1)C([O-])=O

InChI Key InChIKey=PJZKIVWIYBFBRS-LAGNOHSDSA-M

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450612   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450612(Sodium (2S,3R)-3-((R or S)-2-(1-(2,5-bis(trifluoro...)
Affinity DataEC50:  99nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450612(Sodium (2S,3R)-3-((R or S)-2-(1-(2,5-bis(trifluoro...)
Affinity DataEC50:  35nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent