BDBM450710 2-({4-[2-(2-chlorophenyl)-2-methyl-1,3- benzodioxol-4-yl]piperidin-1-yl}methyl)-1- (2-methoxyethyl)-1H-benzimidazole-6- carboxylic acid, formate salt::US10676465, Example 86

SMILES COCCn1c(CN2CCC(CC2)c2cccc3OC(C)(Oc23)c2ccccc2Cl)nc2ccc(cc12)C(O)=O

InChI Key InChIKey=WAZQKMUDFLJHAI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450710   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM450710(2-({4-[2-(2-chlorophenyl)-2-methyl-1,3- benzodioxo...)
Affinity DataEC50:  410nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM450710(2-({4-[2-(2-chlorophenyl)-2-methyl-1,3- benzodioxo...)
Affinity DataEC50:  24nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent