BDBM450861 US10676469, Compound 119::US11124504, Cpd. No. 119

SMILES Cc1noc(n1)-c1c(C)c2cc(C)cc(F)c2nc1N1CCC(CC1)N[C@@H]1CCCOC1

InChI Key InChIKey=KFQBVNZJERTAAZ-GOSISDBHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450861   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450861(US10676469, Compound 119 | US11124504, Cpd. No. 11...)
Affinity DataIC50: <1nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM450861(US10676469, Compound 119 | US11124504, Cpd. No. 11...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450861(US10676469, Compound 119 | US11124504, Cpd. No. 11...)
Affinity DataIC50: >100nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM450861(US10676469, Compound 119 | US11124504, Cpd. No. 11...)
Affinity DataIC50:  55nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent