BDBM450915 US10676469, Compound 218::US10676469, Compound 240::US11124504, Cpd. No. 240

SMILES C[C@@H]1C[C@@H](CCN1c1nc2c(F)cc(C)cc2c(C)c1-c1nc(C)no1)NC1CCOCC1

InChI Key InChIKey=IGOVNQHTXKFANI-DNVCBOLYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 450915   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50:  5.5nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50: >1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50:  5.5nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50:  550nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50:  55nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50: >1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50:  55nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450915(US10676469, Compound 218 | US10676469, Compound 24...)
Affinity DataIC50: >100nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent