BDBM451058 5-(((5-fluoro-2,3-dihydrobenzofuran-4-::US10676479, Example 88

SMILES Cc1nn(CCO)c(C)c1-c1cnc(NCc2c3CCOc3ccc2F)n2cnc(C#N)c12

InChI Key InChIKey=AWOMROMVFXGIAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451058   

LigandPNGBDBM451058(5-(((5-fluoro-2,3-dihydrobenzofuran-4- | US1067647...)
Affinity DataIC50:  3.40nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM451058(5-(((5-fluoro-2,3-dihydrobenzofuran-4- | US1067647...)
Affinity DataIC50:  13nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM451058(5-(((5-fluoro-2,3-dihydrobenzofuran-4- | US1067647...)
Affinity DataIC50:  11.7nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent