BDBM451107 US10676485, Example 17

SMILES CN1CCN(C[C@@H]2COc3ccc(OCc4ccnc(n4)-c4ccc(OC[C@@H]5COCCO5)cc4)c(C[C@@H](Oc4ncnc5sc(C6CCCCC6)c(-c6c(C)c(Cl)c(O2)c(Cl)c6C)c45)C(O)=O)c3)CC1

InChI Key InChIKey=LHGPJQRRVBSMDP-JOVQOBAQSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451107   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM451107(US10676485, Example 17)
Affinity DataKi:  0.0900nMAssay Description:The ability of the exemplary MCL-1 inhibitors of Examples 1 through 151 to bind MCL-1 was demonstrated using the Time Resolved-Fluorescence Resonance...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM451107(US10676485, Example 17)
Affinity DataKi:  4.11nMAssay Description:The ability of the exemplary MCL-1 inhibitors of Examples 1 through 151 to bind MCL-1 was demonstrated using the Time Resolved-Fluorescence Resonance...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent