BDBM451108 US10676485, Example 18

SMILES COc1ccccc1-c1nccc(COc2ccc3OC[C@@H](CN4CCN(C)CC4)Oc4c(Cl)c(C)c(-c5c(C[C@@H]6COCCO6)sc6ncnc(O[C@H](Cc2c3)C(O)=O)c56)c(C)c4Cl)n1

InChI Key InChIKey=METSGICPNWVTFM-XXUJLVSLSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451108   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM451108(US10676485, Example 18)
Affinity DataKi:  0.111nMAssay Description:The ability of the exemplary MCL-1 inhibitors of Examples 1 through 151 to bind MCL-1 was demonstrated using the Time Resolved-Fluorescence Resonance...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM451108(US10676485, Example 18)
Affinity DataKi:  0.240nMAssay Description:The ability of the exemplary MCL-1 inhibitors of Examples 1 through 151 to bind MCL-1 was demonstrated using the Time Resolved-Fluorescence Resonance...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent