BDBM454991 US10730874, Compound I-15::US11352356, Compound I-15

SMILES Clc1ccn2cnc(CNC(=O)c3cnn(Cc4cn5nc(ccc5n4)C4CC4)c3)c2c1

InChI Key InChIKey=ODQXINWZNJUUAM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454991   

TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM454991(US10730874, Compound I-15 | US11352356, Compound I...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM454991(US10730874, Compound I-15 | US11352356, Compound I...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent