BDBM4577 4-anilinoquinazoline deriv. 10j::N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]but-2-ynamide
SMILES COC[C@@H]1CCCN1CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
InChI Key InChIKey=RLNZIWVIDMGNEN-FQEVSTJZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 4577
Affinity DataIC50: 117nMAssay Description:The HER-2 kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMpH: 7.4 T: 2°CAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair