BDBM4600 (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-3-(dimethylamino)prop-2-enamide::4-anilinoquinazoline deriv. 25a

SMILES CN(C)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=FSGPEDYXNUKDAG-CMDGGOBGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4600   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4600((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-3...)
Affinity DataIC50:  2.57E+4nMAssay Description:The HER-2 kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4600((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-3...)
Affinity DataIC50:  250nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed