BDBM4606 1,6-naphthyridine deriv. 8::1-(7-amino-3-phenyl-1,6-naphthyridin-2-yl)-3-tert-butylurea::N-(7-Amino-3-phenyl-1,6-naphthyridin-2-yl)-N-tert-butyl urea

SMILES CC(C)(C)NC(=O)Nc1nc2cc(N)ncc2cc1-c1ccccc1

InChI Key InChIKey=KRTWNZSIDWGFLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4606   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4606(1,6-naphthyridine deriv. 8 | 1-(7-amino-3-phenyl-1...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4606(1,6-naphthyridine deriv. 8 | 1-(7-amino-3-phenyl-1...)
Affinity DataIC50:  4.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4606(1,6-naphthyridine deriv. 8 | 1-(7-amino-3-phenyl-1...)
Affinity DataIC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed