BDBM4610 1,6-naphthyridine deriv. 12::3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine

SMILES COc1cc(OC)cc(c1)-c1cc2cnc(N)cc2nc1N

InChI Key InChIKey=XXQRJTXNOCEQLF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4610   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4610(1,6-naphthyridine deriv. 12 | 3-(3,5-dimethoxyphen...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4610(1,6-naphthyridine deriv. 12 | 3-(3,5-dimethoxyphen...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4610(1,6-naphthyridine deriv. 12 | 3-(3,5-dimethoxyphen...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed