BDBM4611 1,6-naphthyridine deriv. 13::1-[7-amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-3-methylurea::N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-methylurea

SMILES CNC(=O)Nc1nc2cc(N)ncc2cc1-c1cc(OC)cc(OC)c1

InChI Key InChIKey=QBBDXJPRXHFUCL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4611   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4611(1,6-naphthyridine deriv. 13 | 1-[7-amino-3-(3,5-di...)
Affinity DataIC50:  95nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4611(1,6-naphthyridine deriv. 13 | 1-[7-amino-3-(3,5-di...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Auckland

LigandPNGBDBM4611(1,6-naphthyridine deriv. 13 | 1-[7-amino-3-(3,5-di...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed