BDBM461121 US10774053, Compound 341::US11352329, COMPD # 341
SMILES CC(C)(C)C[C@@]1(NC(=N)N([C@H](COC(=O)N[C@@H]2CC22CC2)c2ccc(Cl)c(c2)-n2ncnc2C(F)F)C1=O)c1ccc(cc1)-c1cnn(c1)C(F)F
InChI Key InChIKey=QNKGCZRNGSRJSA-AZAGJHQNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 461121
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 3.20nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataEC50: 8.54nMAssay Description:Assay protocol is identical to that described for the MT-4 antiviral assay with the following changes: Each drug is run in 2 series of quadruplicates...More data for this Ligand-Target Pair