BDBM4632 Anilinoquinazoline deriv. 15::N-(4-Chloro-2-fluorophenyl)-7-(2-methoxyethoxy)-4-quinazolinylamine::N-(4-chloro-2-fluorophenyl)-7-(2-methoxyethoxy)quinazolin-4-amine

SMILES COCCOc1ccc2c(Nc3ccc(Cl)cc3F)ncnc2c1

InChI Key InChIKey=PMDSTJDYKPKKER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4632   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4632(Anilinoquinazoline deriv. 15 | N-(4-Chloro-2-fluor...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4632(Anilinoquinazoline deriv. 15 | N-(4-Chloro-2-fluor...)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM4632(Anilinoquinazoline deriv. 15 | N-(4-Chloro-2-fluor...)
Affinity DataIC50:  150nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed