BDBM465646 US10793568, Compound I-297

SMILES OC(=O)c1cc(OC2CC2)c2nc(sc2c1)N1[C@@H]2C[C@@H](OCc3c(onc3-c3c(Cl)cccc3Cl)C3CC3)[C@@H](C2)C1=O

InChI Key InChIKey=SCBOXUHTHGRECJ-LUQKVYGDSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465646   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465646(US10793568, Compound I-297)
Affinity DataEC50:  1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent