BDBM46695 2-(3-chlorophenyl)-1,2-benzothiazol-3-one::MLS-0390880.0001::cid_13186954

SMILES Clc1cccc(c1)-n1sc2ccccc2c1=O

InChI Key InChIKey=BFXLBNPIMRUZFI-UHFFFAOYSA-N

Data  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 46695   

TargetPhosphomannomutase 2(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  5.96E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhosphoethanolamine/phosphocholine phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  5.21E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  3.43E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlucose-6-phosphate 1-dehydrogenase(Leuconostoc mesenteroides)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50: >2.50E+4nMAssay Description:Excerpt from MH082340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African sleep...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of phosphomannose isomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitochondrial peptide methionine sulfoxide reductase(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataEC50: >1.04E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhosphoethanolamine/phosphocholine phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of PHOSPHO1 phosphoethanolamine activity (unknown origin) assessed as amount of inorganic phosphate release after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphomannomutase 2(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PMM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46695(2-(3-chlorophenyl)-1,2-benzothiazol-3-one | MLS-03...)
Affinity DataIC50:  1.90E+3nMAssay Description:Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African slee...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay