BDBM47045 US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid::US8906933, (S)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid::US8906933, 2-hydroxy-4-(6-(1-methyl-1H-pyrazol-4-yl)-2-oxo-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid

SMILES Cn1cc(cn1)C1NC(=O)NC(C1c1ccsc1)c1ccc(C(O)=O)c(O)c1

InChI Key InChIKey=KQQKKFDAXNYXTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47045   

TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
N30 Pharmaceuticals

US Patent
LigandPNGBDBM47045(US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  39nMpH: 7.4 T: 2°CAssay Description:Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
N30 Pharmaceuticals

US Patent
LigandPNGBDBM47045(US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  4.25E+3nMpH: 7.4 T: 2°CAssay Description:Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
N30 Pharmaceuticals

US Patent
LigandPNGBDBM47045(US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent