BDBM47122 US8598155, 10::US8598155, 3

SMILES CNc1ncnn2c(C)nc(-c3cnn(C)c3-c3ccc(cc3)C(F)(F)F)c12

InChI Key InChIKey=VZDDRXKVJMUSEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47122   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM47122(US8598155, 10 | US8598155, 3)
Affinity DataIC50:  1.25nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM47122(US8598155, 10 | US8598155, 3)
Affinity DataIC50:  1.30nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair
In DepthDetails US Patent