BDBM47298 BDBM64616::US9023354, AD4-10960

SMILES CCC(=O)NC(c1cccs1)c1cc([N+]([O-])=O)c2cccnc2c1O

InChI Key InChIKey=DEXNORPUTBBNSC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 47298   

TargetProthrombin(Bos taurus (Bovine))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50:  4.03E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50:  1.70E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-1 assessed as conjugated diene product formation using arachidonic acid by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of 12-lipoxygenase in human platelets assessed as reduction of PAR1-AP-induced 12 HETE production by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HIV-1 integrase 3'-processing activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50:  800nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed