BDBM47816 6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid (3-methoxy-propyl)-amide::MLS001029502::SMR000425486::cid_3729555

SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23

InChI Key InChIKey=LXUKGKQDBOPMHC-UHFFFAOYSA-N

Data  4 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 47816   

TargetRegulator of G-protein signaling 8(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  4.25E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRegulator of G-protein signaling 7(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  1.74E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRegulator of G-protein signaling 19(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  3.87E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRegulator of G-protein signaling 16(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  5.69E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRegulator of G-protein signaling 4(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  3.08E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataEC50:  3.48E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-9(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataIC50:  1.26E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataIC50:  1.57E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM47816(6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...)
Affinity DataIC50:  2.25E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay