BDBM4859 1-(4-Chloroanilino)-4-[2,6-dimethylpyridin-4-ylmethyl]-phthalazine::CGP79787 Analog 44::N-(4-chlorophenyl)-4-[(2,6-dimethylpyridin-4-yl)methyl]phthalazin-1-amine

SMILES Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)cc(C)n1

InChI Key InChIKey=PXVHGHAKRNHTTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4859   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4859(1-(4-Chloroanilino)-4-[2,6-dimethylpyridin-4-ylmet...)
Affinity DataIC50: >1.00E+4nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4859(1-(4-Chloroanilino)-4-[2,6-dimethylpyridin-4-ylmet...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed