BDBM4860 1-(4-Chloroanilino)-4-(4-pyridylmethylamino)phthalazine::1-N-(4-chlorophenyl)-4-N-(pyridin-4-ylmethyl)phthalazine-1,4-diamine::CGP79787 Analog 51

SMILES Clc1ccc(Nc2nnc(NCc3ccncc3)c3ccccc23)cc1

InChI Key InChIKey=HXPCKJPCDLSTDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4860   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4860(1-(4-Chloroanilino)-4-(4-pyridylmethylamino)phthal...)
Affinity DataIC50:  4.70E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4860(1-(4-Chloroanilino)-4-(4-pyridylmethylamino)phthal...)
Affinity DataIC50:  2.60E+3nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed