BDBM4866 CGP79787 Analog 49::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)pyrido[3,4-d]pyridazin-1-amine

SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3cnccc23)cc1

InChI Key InChIKey=DJUQYZCHZIOROJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4866   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4866(CGP79787 Analog 49 | N-(4-chlorophenyl)-4-(pyridin...)
Affinity DataIC50:  610nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4866(CGP79787 Analog 49 | N-(4-chlorophenyl)-4-(pyridin...)
Affinity DataIC50:  230nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed