BDBM4873 1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine::CGP79787 Analog 58::N-(4-phenylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES C(c1ccncc1)c1nnc(Nc2ccc(cc2)-c2ccccc2)c2ccccc12

InChI Key InChIKey=FWAKGUVZUVZGNE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4873   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4873(1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine...)
Affinity DataIC50:  230nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4873(1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine...)
Affinity DataIC50:  1.40E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4873(1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine...)
Affinity DataIC50:  1.40E+3nMAssay Description:The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4873(1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine...)
Affinity DataIC50:  200nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed