BDBM49255 2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindole::2-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::MLS000066641::SMR000082547::cid_1236969

SMILES Fc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1

InChI Key InChIKey=OTMSGGRGWSIHPW-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 49255   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49255(2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindo...)
Affinity DataEC50:  125nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49255(2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindo...)
Affinity DataIC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49255(2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindo...)
Affinity DataEC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49255(2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindo...)
Affinity DataIC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49255(2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindo...)
Affinity DataEC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay