BDBM49356 2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole::2-Phenyl-5-p-tolyl-[1,3,4]oxadiazole::2-phenyl-5-(4-methylphenyl)-1,3,4-oxadiazole (2b)::2-phenyl-5-(p-tolyl)-1,3,4-oxadiazole::MLS000120832::SMR000118227::cid_259997

SMILES Cc1ccc(cc1)-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=UHQIKTAVLMIABA-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49356   

TargetCathepsin L(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM49356(2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...)
Affinity DataKi:  1.36E+3nM ΔG°:  -8.32kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM49356(2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...)
Affinity DataKi:  2.55E+3nM ΔG°:  -7.93kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM49356(2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...)
Affinity DataKi:  1.13E+4nM ΔG°:  -7.02kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49356(2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...)
Affinity DataEC50:  3.44E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay